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MYP_024760
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Basic Information
L2 (Ala33 substitution mutant of LALF (32-51))
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C129H196N38O23
Standard
Sequence
HARIKPTFRRLKWKYKGKFW
Physicochemical Analysis
2647.18 Da
11.76
7.84
7.58
0.3921
-1.31
0.59
-0.38
23.56
44.00
0.2500
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1023.95
-3.48
39.0
32.0
87.0
190.0
9.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0169208 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23401744 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23401744/
RECORD: Rec_0237346 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID23401744 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23401744/
RECORD: Rec_0293043 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
LALF-derived
6850
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
None
N-term detail: Biotinylation
Bio-Activity Profile
Cell-penetrating peptide
Hep2; TC1; CasKi; SiHa; PBMC
Cellular uptake assay
PMID19908203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19908203/
RECORD: Rec_0356517 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
Acetylation
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID29601540 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29601540/
RECORD: Rec_0372778 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
Acetylation
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID29601540 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29601540/
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