MYP_024757
MS2
Anticancer
Antimicrobial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Standard
23 amino acids
C125H194N36O37
Standard
RPEIWLTQSLQRLGDEINAYYAR
2793.10 Da
6.18
-0.24
-0.44
-0.0102
-0.76
0.71
-0.16
93.27
93.48
0.1304
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1218.31
-10.13
43.0
37.0
90.0
198.0
5.0
25.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0069117
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Anticancer
Cytotoxic
Mcl-1-targeting
Mcl-1/Myc 2640 cells
700 nM
EC50 (whole-cell BH3 profiling; JC-1 mitochondrial depolarization)
RECORD: Rec_0260663
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
5/6-fluorescein labeling
Amidation
Bio-Activity Profile
Anticancer
Protein-binding
Mcl-1-targeting
Mcl-1
1.5±1.2 nM
Kd (fluorescence anisotropy)