Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC731H1218N220O247S9

DescriptionStandard

        MKSLWVTLAVFLLLVPLVSGNWYAPRCANKKGRCRTKCRTREMAASPTVGSCGQKKTCCIKRDGSAPTFCSETTKATNSLNTVSQAAGGTPGAVASPSAAATTTTATSAAAAAVAVASTTTTPASAGLATPTTTSAAGAPLRVASSTASSAAAASAAASVPAAASAAASAAAAASASSAGAAA
    

Molecular Weight17329.40 Da

Isoelectric Point (pI)10.01

Net Charge (pH 7.0)11.43

Net Charge (pH 7.4) 11.09

Charge Density (pH 7.0) 0.0625

GRAVY Index0.28

Hydrophobic Moment 0.61

Boman Index0.15

Instability Index32.05

Aliphatic Index 67.70

Aromaticity 0.0273

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7346.83

LogP -118.29

H-bond Donors 272.0

H-bond Acceptors 268.0

Rotatable Bonds 541.0

Heavy Atoms 1207.0

Ring Count 17.0

Amide Bonds 188.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048007 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence