Peptide Database

Peptide NameCalcitonin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC130H197N39O42S2

DescriptionStandard

        CDGVSTCWLHELGNSVHATAGGKQNVGFGP
    

Molecular Weight3042.32 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.42

Charge Density (pH 7.0) -0.0361

GRAVY Index-0.14

Hydrophobic Moment 0.43

Boman Index0.18

Instability Index31.60

Aliphatic Index 61.67

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1282.39

LogP -17.16

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 95.0

Heavy Atoms 213.0

Ring Count 6.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385148 VERIFIED: YES

Provenance & Taxonomy

OrganismCiona intestinalis [Animal]

FamilyCalcitonin

Tax ID7719

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Osteogenic Promotes osteoblast differentiation and mineralization

TargetMC3T3-E1 pre-osteoblast cells

Methodosteoblast differentiation/mineralization assay (ALP; Alizarin Red S)