Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC875H1456N258O256S11

DescriptionStandard

        MKKAKGAIIACAIALIIANVKSTDPEIRTSAEGLALIAKFEGCSLRAYKCPNDVLTVGIGSTAAGGEKIIAGKIYTNEEIAARYKKDIKAVEHCLNQHFNGALMTQKQFDAMVSLGLNVGCGNLKTYYSTRLGKRLQTTIHKRAQAKQFAEMCERITDFDRSGGRKVRGLTIRRQEEKALCLK
    

Molecular Weight20039.21 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)13.71

Net Charge (pH 7.4) 13.18

Charge Density (pH 7.0) 0.0749

GRAVY Index-0.21

Hydrophobic Moment 0.76

Boman Index-0.04

Instability Index29.96

Aliphatic Index 89.18

Aromaticity 0.0546

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8388.04

LogP -100.23

H-bond Donors 302.0

H-bond Acceptors 284.0

Rotatable Bonds 700.0

Heavy Atoms 1400.0

Ring Count 15.0

Amide Bonds 196.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0254392 VERIFIED: YES

Provenance & Taxonomy

OrganismIrtavirus F108 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0279547 VERIFIED: NO

Provenance & Taxonomy

OrganismPasteurella multocida [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

RECORD: Rec_0380141 VERIFIED: NO

Provenance & Taxonomy

OrganismPasteurella multocida subsp. multocida P1062 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence