Peptide Database

Peptide NameAstexin-2 (Class II lasso peptide) (Ribosomally synthesized and post-translationally modified peptide) (RiPP)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC225H390N72O72S

DescriptionStandard

        MTKRTTIAARRVGLIDLGKATRQTKGLTQIQALDSVSGQFRDQLGLSAD
    

Molecular Weight5288.01 Da

Isoelectric Point (pI)10.88

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.28

Charge Density (pH 7.0) 0.0715

GRAVY Index-0.32

Hydrophobic Moment 0.54

Boman Index-0.12

Instability Index25.40

Aliphatic Index 93.67

Aromaticity 0.0204

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2394.40

LogP -30.16

H-bond Donors 86.0

H-bond Acceptors 77.0

Rotatable Bonds 186.0

Heavy Atoms 370.0

Ring Count 1.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249713 VERIFIED: YES

Provenance & Taxonomy

OrganismAsticcacaulis excentricus [Bacterium]

Tax ID573065

Structure & Mods

Configlasso peptide topology [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic