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MYP_024623
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Basic Information
PGLa-H
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C50H95N13O11
Standard
Sequence
KIAKVALKAL
Physicochemical Analysis
1054.37 Da
10.30
2.76
2.55
0.2757
1.00
0.67
0.19
-16.47
176.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
403.28
-1.00
14.0
14.0
38.0
74.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0267242 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
23.6 μg/mL
MIC
PaperIsolation and characterisation of a new antimicrobial peptide from the skin of Xenopus laevis
RECORD: Rec_0310521 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
PGLa
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
8.3 μM
MIC
PaperF. Hou et al. / International Journal of Antimicrobial Agents 38 (2011) 510-515. Isolation and characterisation of a new antimicrobial peptide from the skin of Xenopus laevis Evidence URLhttps://www.uniprot.org/uniprotkb/Q91826/entry
RECORD: Rec_0322308 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID22014884;1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22014884/
RECORD: Rec_0333681 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
PGLa
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
22.4 μM
MIC
PaperF. Hou et al. / International Journal of Antimicrobial Agents 38 (2011) 510-515. Isolation and characterisation of a new antimicrobial peptide from the skin of Xenopus laevis Evidence URLhttps://www.uniprot.org/uniprotkb/Q91826/entry
RECORD: Rec_0342174 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
8.7 μg/mL
MIC
PaperIsolation and characterisation of a new antimicrobial peptide from the skin of Xenopus laevis
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