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MYP_024623
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Basic Information
PGLa-H
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C50H95N13O11
Standard
Sequence
KIAKVALKAL
Physicochemical Analysis
1054.37 Da
10.30
2.76
2.55
0.2757
1.00
0.67
0.19
-16.47
176.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
403.28
-1.00
14.0
14.0
38.0
74.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0227866 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
8.7 μg/mL
MIC
PMID22014884;1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22014884/
RECORD: Rec_0249684 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
14.4 μg/mL
MIC
PaperIsolation and characterisation of a new antimicrobial peptide from the skin of Xenopus laevis
RECORD: Rec_0251227 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA)
67.8 μg/mL
MIC
PMID22014884;1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22014884/
RECORD: Rec_0256627 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0258157 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
8355
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
14.4 μg/mL
MIC
PMID22014884;1717472 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22014884/
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