Peptide Database

Peptide NameDNA dC->dU-editing enzyme APOBEC-3G

Function Ontology

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HBV

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length384 amino acids

Chemical FormulaC2104H3117N573O571S26

DescriptionStandard

        MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
    

Molecular Weight46407.44 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.0125

GRAVY Index-0.61

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index40.09

Aliphatic Index 62.97

Aromaticity 0.1589

Extinction Coeff. Reduced 106800.00

Extinction Coeff. Oxidized 107675.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0384989 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyAPOBEC

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Thr32, Thr218

Bio-Activity Profile

Function

Antiviral Replication inhibitor Anti-HBV

TargetHepatitis B virus(HBV)