Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length245 amino acids

Chemical FormulaC1245H1897N283O373S8

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFRPFIDLDLKGVAFPAGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNITIAEEVKSGNSFVFSLFFFLQTCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNVFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight27053.57 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-15.14

Net Charge (pH 7.4) -15.48

Charge Density (pH 7.0) -0.0618

GRAVY Index0.35

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index45.29

Aliphatic Index 99.10

Aromaticity 0.1306

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054408 VERIFIED: NO

Provenance & Taxonomy

OrganismCorvus brachyrhynchos [Animal]

FamilyBPI/LBP

Tax ID85066

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria