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MYP_024558
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C40H57N7O10
Standard
Sequence
YIPIQY
Physicochemical Analysis
795.92 Da
5.52
-0.24
-0.45
-0.0403
0.22
0.06
0.42
-9.03
130.00
0.3333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
283.58
0.58
9.0
10.0
21.0
57.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004345 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperDe Gobba C., Tompa G., Otte J.. Bioactive peptides from caseins released by cold active proteolytic enzymes from Arsukibacterium ikkense. Food Chemistry 165, 205-215. PMID25038668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25038668/
RECORD: Rec_0077775 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
kappa-Casein-derived
9940
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
10 μM
IC50
PaperIdentification of novel angiotensin-converting enzyme-inhibitory peptides from ovine milk proteins by CE-MS and chromatographic techniques | Gomez-Ruiz, JA. et al. | DOI: 10.1002/elps.200700324 Evidence URLhttps://www.uniprot.org/uniprotkb/P02669/entry
RECORD: Rec_0163529 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
10.0
IC50
PaperGomez-Ruiz J. A., Ramos M., Recio I.. Identification of novel angiotensin-converting enzyme-inhibitory peptides from ovine milk proteins by CE-MS and chromatographic techniques. Electrophoresis, 28, 4202-4211.
RECORD: Rec_0254616 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]; Gallus gallus [Animal]; Bos taurus [Animal]
9940; 9031; 9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperIsolation and characterization of peptides with antihypertensive activity in foodstuffs PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0267737 VERIFIED: NO
Provenance & Taxonomy
Ovine milk [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
10.0 μM
IC50
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