Peptide Database

Peptide NameDioicin-1 (Ribosome-inactivating protein; rRNA N-glycosidase; Plant defense)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC108H159N23O37

DescriptionStandard

        ANIVFDVESATTGTYSTFLTSF
    

Molecular Weight2371.55 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.39

Charge Density (pH 7.0) -0.1001

GRAVY Index0.48

Hydrophobic Moment 0.27

Boman Index0.32

Instability Index37.91

Aliphatic Index 70.91

Aromaticity 0.1818

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 974.18

LogP -11.57

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 72.0

Heavy Atoms 168.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337475 VERIFIED: YES

Provenance & Taxonomy

OrganismPhytolacca dioica [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0345245 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic