‹ ›
MYP_024528
← PREVIOUS NEXT → BACK
Basic Information
Indolocidin-ac
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Virucidal activity
Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
13 amino acids
C100H131N25O14
Standard
Sequence
ILPWKWPWWPWRR
Physicochemical Analysis
1907.27 Da
12.00
2.76
2.55
0.2122
-1.07
0.45
0.02
76.28
60.00
0.3846
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
614.92
4.10
23.0
17.0
48.0
139.0
13.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0376464 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Indolicidin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Virucidal
Herpes simplex virus 1 (Virucidal on progeny virions); Vero
Viral titer
PaperPeptide inhibitors against herpes simplex virus infections. | Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M. | J Pept Sci. 2013 | PMID:23389903 PMID23389903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23389903/
RECORD: Rec_0381097 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/19038369/ PMID19038369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19038369/
RECORD: Rec_0388798 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Indolicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
310 μg/mL
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/16997878/ PMID16997878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16997878/
RECORD: Rec_0395038 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
0.007 %
MIC
PaperPubMed PMID: 1537821 | PubMed PMID: 11123901 | PubMed PMID: 12074933 PMID1537821;11123901;12074933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1537821/
RECORD: Rec_0412806 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
H-1299
270 μg/mL
LD50
PaperShort bioactive peptides Evidence URLhttps://patents.google.com/patent/US6875744B2/en PatentUS6875744B2
FIRST PREV 1 ... 15 16 17 18 NEXT LAST
Showing 5 records on this page · Page 17 of 18