Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 24

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC448H726N144O135S8

DescriptionStandard

        MRTLALLAALLLLAFHAQAEPLGEKDDQVPAQDQPGADVQGMTISFEGAERSTRDAAGSRPGLICHCSSFCRRPYREEGICTRGQPKRFCCRRGPR
    

Molecular Weight10545.96 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.47

Hydrophobic Moment 0.66

Boman Index-0.14

Instability Index49.54

Aliphatic Index 66.25

Aromaticity 0.0521

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4489.63

LogP -52.24

H-bond Donors 163.0

H-bond Acceptors 148.0

Rotatable Bonds 347.0

Heavy Atoms 735.0

Ring Count 14.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218898 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal