Peptide Database

Peptide NameConotoxin Cl14.10

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC169H253N41O48S4

DescriptionStandard

        HVTCFYVKFGCKHTECITTIVFCWQTASDISSV
    

Molecular Weight3755.32 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.10

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0032

GRAVY Index0.52

Hydrophobic Moment 0.47

Boman Index0.25

Instability Index43.44

Aliphatic Index 73.64

Aromaticity 0.1515

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1419.47

LogP -12.88

H-bond Donors 55.0

H-bond Acceptors 54.0

Rotatable Bonds 117.0

Heavy Atoms 262.0

Ring Count 8.0

Amide Bonds 33.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0051591 VERIFIED: NO

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0379760 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic