Peptide Database

Peptide NameInsulin-like growth factor II-B

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC324H506N96O107S6

DescriptionStandard

        YRPTETLCGGELVDTLQFVCGDRGFYFSTNNGRSNRRSNRGIVEECCFRSCDLELLETYCAKPSKNE
    

Molecular Weight7650.45 Da

Isoelectric Point (pI)5.40

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0190

GRAVY Index-0.66

Hydrophobic Moment 0.77

Boman Index-0.19

Instability Index56.37

Aliphatic Index 55.22

Aromaticity 0.1045

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3346.21

LogP -41.01

H-bond Donors 124.0

H-bond Acceptors 112.0

Rotatable Bonds 254.0

Heavy Atoms 533.0

Ring Count 9.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135772 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyInsulin

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0137881 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyInsulin-like growth factor II

Tax ID8355

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-47; 20-60; 46-51

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min