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MYP_024440
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Basic Information
SRP-26 / Ac-RRHWCW-NH2
Antimicrobial
Antiviral
Standard
6 amino acids
C43H58N16O7S
Standard
Sequence
RRHWCW
Physicochemical Analysis
943.09 Da
10.35
1.84
1.57
0.3062
-1.92
0.48
-0.59
170.57
0.00
0.3333
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
392.88
-1.31
17.0
11.0
26.0
67.0
5.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Dengue virus NS2B-NS3 protease inhibitor
Dengue virus type 1 NS2B-NS3 protease
5.0 μM
Ki (NS2B-NS3 protease inhibition assay)
PaperDesign and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases. PMID:23587903. DOI:10.1016/j.bbrc.2013.03.139 PMID23587903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0231441 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Dengue virus NS2B-NS3 protease inhibitor
Dengue virus type 1 NS2B-NS3 protease
5.4 μM
Ki (NS2B-NS3 protease inhibition assay)
PaperDesign and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases. PMID:23587903. DOI:10.1016/j.bbrc.2013.03.139 PMID23587903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0432797 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Dengue virus NS2B-NS3 protease inhibitor
Dengue virus type 2 NS2B-NS3 protease
8.2 μM
Ki (NS2B-NS3 protease inhibition assay)
PaperDesign and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases. PMID:23587903. DOI:10.1016/j.bbrc.2013.03.139 PMID23587903
RECORD: Rec_0432798 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Dengue virus NS2B-NS3 protease inhibitor
Dengue virus type 3 NS2B-NS3 protease
5.2 μM
Ki (NS2B-NS3 protease inhibition assay)
PaperDesign and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases. PMID:23587903. DOI:10.1016/j.bbrc.2013.03.139 PMID23587903
RECORD: Rec_0432799 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Dengue virus NS2B-NS3 protease inhibitor
Dengue virus type 4 NS2B-NS3 protease
6.2 μM
Ki (NS2B-NS3 protease inhibition assay)
PaperDesign and evaluation of substrate-based octapeptide and non substrate-based tetrapeptide inhibitors of dengue virus NS2B-NS3 proteases. PMID:23587903. DOI:10.1016/j.bbrc.2013.03.139 PMID23587903
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