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MYP_024370
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Basic Information
Brevinin-2RE1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Standard
33 amino acids
C156H257N43O48S2
Standard
Sequence
SFLSTFKKLAIDAAKNAGQSVLHTLTCKLDNQC
Physicochemical Analysis
3567.10 Da
8.80
1.53
1.23
0.0462
0.02
0.53
0.05
10.20
91.82
0.0606
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1495.62
-17.27
53.0
53.0
122.0
249.0
3.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0144180 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Shigella dysenteriae
20 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0166045 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli IS218#
20 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0169126 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antifungal
B. pyocyaneus CMCCB1010
1 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0170875 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus IS10#
5 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0175720 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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