Peptide Database

Peptide NameHCV gp (548562), E2-42

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC77H101N19O22S2

DescriptionStandard

        QGSWFGCTWMNSTGF
    

Molecular Weight1708.87 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0167

GRAVY Index-0.20

Hydrophobic Moment 0.21

Boman Index0.29

Instability Index31.17

Aliphatic Index 0.00

Aromaticity 0.2667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 669.40

LogP -7.42

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 50.0

Heavy Atoms 120.0

Ring Count 6.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341729 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHCV(Hepatitis C virus):inhibition of HCVcc infection in Huh7

RECORD: Rec_0380990 VERIFIED: YES