Peptide Database

Peptide NameCurvacin A / sakacin A

Function Ontology

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Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC184H271N53O58S2

DescriptionStandard

        RSYGNGVYCNDDKCWVNWNEANQQIAGIVISGWASGLAG
    

Molecular Weight4217.57 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-1.26

Net Charge (pH 7.4) -1.50

Charge Density (pH 7.0) -0.0322

GRAVY Index-0.29

Hydrophobic Moment 0.40

Boman Index0.12

Instability Index11.05

Aliphatic Index 72.56

Aromaticity 0.1282

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1819.09

LogP -21.14

H-bond Donors 64.0

H-bond Acceptors 59.0

Rotatable Bonds 134.0

Heavy Atoms 297.0

Ring Count 8.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319056 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)