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MYP_024329
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Basic Information
[Lys]3[Lys]11-VmCT1-NH2 (Derived from VmCT1)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C79H122N18O15
Standard
Sequence
FLKALWNVAKKVF
Physicochemical Analysis
1563.93 Da
10.30
2.76
2.55
0.2121
0.70
0.67
0.26
23.88
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
549.46
0.13
19.0
18.0
51.0
112.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0314893 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans MDM8 and Candida tropicalis IOC 4560.
PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0316396 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans MDM8
1.6 μM
MIC
PaperThe effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1 PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0348848 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0355775 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli SBS 363 (MIC=1.6 μmol/L)，Serratia marcescens ATCC 4112
0.2 μM
MIC
PaperThe effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1 PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0419047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Micrococcus luteus A270
0.4 μM
MIC
PaperThe effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1 PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
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