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MYP_024325
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Basic Information
Dermaseptin-PS1, Dermaseptin cDNA
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C143H243N39O39S
Standard
Sequence
ALWKTMLKKLGTVALHAGKAALGAVADTISQ
Physicochemical Analysis
3164.76 Da
10.00
2.88
2.63
0.0929
0.50
0.53
0.24
2.25
116.77
0.0323
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1246.18
-10.60
44.0
44.0
107.0
222.0
3.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160633 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
10 μM
Hemolysis
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0225116 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans NCPF 1467
100 μM
MIC
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0246962 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
100 μM
MBC
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0257334 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
10 μM
MIC
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0277583 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans
100 μM
MIC
PaperNovel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling
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