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MYP_024325
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Basic Information
Dermaseptin-PS1, Dermaseptin cDNA
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C143H243N39O39S
Standard
Sequence
ALWKTMLKKLGTVALHAGKAALGAVADTISQ
Physicochemical Analysis
3164.76 Da
10.00
2.88
2.63
0.0929
0.50
0.53
0.24
2.25
116.77
0.0323
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1246.18
-10.60
44.0
44.0
107.0
222.0
3.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0059784 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
10 μM
MIC
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0071741 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0078830 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
100 μM
MBC
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
RECORD: Rec_0080649 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli
10 μM
MIC
PaperNovel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling
RECORD: Rec_0157132 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human glioblastoma U251-MG
5.419 μM
IC50
PMID30461197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30461197/
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