Peptide Database

Peptide Nameaurein 5.2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC110H194N28O32S

DescriptionStandard

        GLMSSIGKALGGLIVDLVKPKTPAS
    

Molecular Weight2452.95 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0703

GRAVY Index0.60

Hydrophobic Moment 0.47

Boman Index0.29

Instability Index30.55

Aliphatic Index 124.80

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 940.42

LogP -8.83

H-bond Donors 32.0

H-bond Acceptors 35.0

Rotatable Bonds 82.0

Heavy Atoms 171.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077587 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria aurea; Litoria raniformis [Animal]

FamilyAurein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

PaperRozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/