Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length286 amino acids

Chemical FormulaC1432H2272N360O403S9

DescriptionStandard

        MENICQVVTSSVSSKLEPFLQSVPVTAKIDNVAGIDYSLLAPPIATAETLDGQLKGEFFSLAHRSPPPFTPPPLAFPTDHDHMVYLGISDYFFNTAGLVYQQAGVLNLTLRDDMIPKESKFRLTTKYLGTLIPKVARMFPNMTVQLLVRVSSPPRLEVSPAGLALTPALEAQAFAVLPNSSLAPLFLLGMSTNVSVEVGAKSNRLVGQLGLDKLLLELKHSDIGPFSVELMQAVMNFVIPTAVLPKVNERLQKGFPLPLPRHVQLLNLVLQSYQDFLLFGADVQYD
    

Molecular Weight31268.11 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-3.04

Net Charge (pH 7.4) -3.58

Charge Density (pH 7.0) -0.0106

GRAVY Index0.23

Hydrophobic Moment 0.73

Boman Index0.18

Instability Index37.43

Aliphatic Index 108.36

Aromaticity 0.0804

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0362544 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllostomus discolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria