Peptide Database

Peptide NameHNH endonuclease domain protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC515H783N139O140S

DescriptionStandard

        MKSFYQFLAFTDTLWLEVSQYPELIAQFSSGNQTRIKQGLTAKAPLEGWHYGPKEIVKKFQIHHRVAIEYGGSVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight11193.64 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.95

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.45

Hydrophobic Moment 0.54

Boman Index-0.01

Instability Index50.30

Aliphatic Index 86.21

Aromaticity 0.1368

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4507.46

LogP -34.52

H-bond Donors 157.0

H-bond Acceptors 148.0

Rotatable Bonds 367.0

Heavy Atoms 795.0

Ring Count 24.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066775 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli 908519 [Bacterium]

FamilyPyocin/Colicin

Tax ID1268991

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal