Peptide Database

Peptide NameConotoxin BeTXIb

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC68H100N18O18S6

DescriptionStandard

        CCELPCHGCVPCCWP
    

Molecular Weight1650.02 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.21

Net Charge (pH 7.4) -1.55

Charge Density (pH 7.0) -0.0806

GRAVY Index0.68

Hydrophobic Moment 0.09

Boman Index0.29

Instability Index50.54

Aliphatic Index 45.33

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 526.12

LogP -3.83

H-bond Donors 22.0

H-bond Acceptors 24.0

Rotatable Bonds 42.0

Heavy Atoms 110.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316895 VERIFIED: NO

Provenance & Taxonomy

OrganismConus betulinus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-9; 2-12; 6-13

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0345348 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 20.0%, E 0.0%, T 46.7%, C 33.3% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic