Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC918H1437N249O249S9

DescriptionStandard

        PTPLPVAHESMLLVAVTDFVANSAAFTYFMAGAMRRNITSDMLPRRFPLQLRTKSLGLFAPQLQEHYPDQPMELQLSARRQPLFSCRPDALHGTLFASAEAFVVLPNATRVPAFLLNIDANVTGKPTLTGNRLGGTVKLTGCVGGSAWAQGLPVPQVKNLENLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight20234.33 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)4.28

Net Charge (pH 7.4) 3.94

Charge Density (pH 7.0) 0.0230

GRAVY Index0.10

Hydrophobic Moment 0.60

Boman Index0.14

Instability Index53.55

Aliphatic Index 90.75

Aromaticity 0.0860

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7793.92

LogP -87.98

H-bond Donors 266.0

H-bond Acceptors 266.0

Rotatable Bonds 633.0

Heavy Atoms 1425.0

Ring Count 42.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214856 VERIFIED: NO

Provenance & Taxonomy

OrganismHalcyon senegalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria