Peptide Database

Peptide NameEsculentin-2-b02

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC376H609N97O111S5

DescriptionStandard

        MFTLKKPMLVLFFLGTISLSLCEEERSADEDDGEEEVKRGLFSIFKTAAKFVGKNLLKQAGKAGLEHLACKAKNEC
    

Molecular Weight8424.77 Da

Isoelectric Point (pI)6.57

Net Charge (pH 7.0)-0.42

Net Charge (pH 7.4) -0.77

Charge Density (pH 7.0) -0.0056

GRAVY Index-0.12

Hydrophobic Moment 0.67

Boman Index0.02

Instability Index39.04

Aliphatic Index 87.37

Aromaticity 0.0789

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3368.19

LogP -28.37

H-bond Donors 118.0

H-bond Acceptors 117.0

Rotatable Bonds 297.0

Heavy Atoms 589.0

Ring Count 8.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337883 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0366289 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyEsculentin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial