Peptide Database

Peptide NameToxin Bs6

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC168H279N57O48S8

DescriptionStandard

        GVPINVKCRGSPQCIQPCRDAGMRFGKCMNGKCHCTPQ
    

Molecular Weight4121.89 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.1259

GRAVY Index-0.49

Hydrophobic Moment 0.58

Boman Index-0.13

Instability Index49.94

Aliphatic Index 38.42

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1690.51

LogP -22.19

H-bond Donors 62.0

H-bond Acceptors 62.0

Rotatable Bonds 134.0

Heavy Atoms 281.0

Ring Count 6.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008097 VERIFIED: NO

Provenance & Taxonomy

OrganismButhus sindicus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0432776 VERIFIED: YES

Provenance & Taxonomy

OrganismButhus sindicus [Animal]; synthetic construct [Synthetic]

Structure & Mods

Bio-Activity Profile

Function

Toxin Potassium channel inhibitor

Targethuman Kv1.3 potassium channel

Activity0.89 nM

MethodIC50 by electrophysiological potassium-channel current assay

RECORD: Rec_0432777 VERIFIED: YES

Provenance & Taxonomy

OrganismButhus sindicus [Animal]; synthetic construct [Synthetic]

Structure & Mods

Bio-Activity Profile

Function

Toxin Potassium channel modulator

Targethuman Kv7.1 potassium channel

Methodelectrophysiological potassium-channel current assay