Peptide Database

Peptide NameBeta-defensin 113

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC433H679N115O116S9

DescriptionStandard

        MKILCIFLTFVFTVSCGPSVPQKKTREVAERKRECQLVRGACKPECNSWEYVYYYCNVNPCCAVWEYQKPIINKITSKLHQK
    

Molecular Weight9640.31 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)6.51

Net Charge (pH 7.4) 6.10

Charge Density (pH 7.0) 0.0794

GRAVY Index-0.26

Hydrophobic Moment 0.59

Boman Index-0.04

Instability Index42.70

Aliphatic Index 74.76

Aromaticity 0.1220

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3750.02

LogP -30.28

H-bond Donors 137.0

H-bond Acceptors 133.0

Rotatable Bonds 315.0

Heavy Atoms 673.0

Ring Count 18.0

Amide Bonds 89.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0413296 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KQ7/entry; https://bblserver.org.in/ampdb/