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MYP_024014
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Basic Information
GHaR6R (variant of temporin-GHaR)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C72H119N23O15
Standard
Sequence
FLQRIRGALGRLF
Physicochemical Analysis
1546.86 Da
12.00
2.76
2.56
0.2123
0.42
0.61
0.01
21.25
127.69
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
641.31
-3.78
24.0
18.0
52.0
110.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218531 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Staphylococcus aureus
MIC
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0221341 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Methicillin-resistant Staphylococcus aureus
Bio-Activity Profile
Antimicrobial Antibacterial
methicillin-resistant Staphylococcus aureus-4
12.5 μM
MIC
PMID35538042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35538042/
RECORD: Rec_0253933 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
MIC
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0261737 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells (hRBCs)
PaperTemporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis PMID33291521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33291521/
RECORD: Rec_0312422 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Methicillin-resistant Staphylococcus aureus
Bio-Activity Profile
Antimicrobial Antibacterial
methicillin-resistant Staphylococcus aureus-2
12.5 μM
MIC
PMID35538042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35538042/
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