Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC266H423N73O91S8

DescriptionStandard

        MMSNNQFDLDIQVSKNVGKIQPQYTSWSYCTTGCITGPNCNSSECATVPCKTTTNKCL
    

Molecular Weight6356.16 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.44

Net Charge (pH 7.4) 0.12

Charge Density (pH 7.0) 0.0076

GRAVY Index-0.41

Hydrophobic Moment 0.49

Boman Index-0.01

Instability Index37.87

Aliphatic Index 50.34

Aromaticity 0.0690

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2682.00

LogP -37.74

H-bond Donors 96.0

H-bond Acceptors 100.0

Rotatable Bonds 206.0

Heavy Atoms 438.0

Ring Count 8.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203554 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus sp. M-152 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear lantibiotic precursor [Linear]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

MethodQualitative functional evidence