Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC493H789N131O133S9

DescriptionStandard

        MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRINEVREALCENGRYCCLNINELEACKKITKPPHPKPATFALTLPQDYVTIIENFPSL
    

Molecular Weight10967.92 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.17

Charge Density (pH 7.0) 0.0381

GRAVY Index-0.08

Hydrophobic Moment 0.72

Boman Index0.04

Instability Index40.05

Aliphatic Index 95.47

Aromaticity 0.0842

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4240.79

LogP -32.43

H-bond Donors 148.0

H-bond Acceptors 148.0

Rotatable Bonds 361.0

Heavy Atoms 766.0

Ring Count 18.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039397 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence