Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length583 amino acids

Chemical FormulaC2691H4273N815O855S9

DescriptionStandard

        MSGGDGIGHNSGAHSTGGVNGSSSGRGGSSSGGGNNPNSGPGWGTTHTPDGHDIHNYNPGEFGGGGHKPGGNSGNHSGGTGDGQPSGAAMAFGFPALVPAGAGGLAVTVSGDALAAAIADVLAVLKGPFKFGAWGIALYGILPTEIAKDDPRMMSKIVTSLPADAVTESPVSSLPLGQATISVTKRVTDVVKDERQHIAVVAGGPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNASAMTALPRGVTDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTSEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQAEFNAAEKEKADADAALNVALESRKQKEQKAKDASDKLDKENKRNHPGKATGKGQPVGDKWLEDAGKEAGAPVPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPELIKQLKNQNKTNVQKGKAPFAKKKDQVGGRERFELHHNKPISQDGGVYDMDNIRVTTPKRHIDIHRGK
    

Molecular Weight62011.25 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)4.24

Net Charge (pH 7.4) 2.90

Charge Density (pH 7.0) 0.0073

GRAVY Index-0.71

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index35.96

Aliphatic Index 63.31

Aromaticity 0.0515

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359720 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli