Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC365H558N92O92S8

DescriptionStandard

        MWTFLFLFAVFFFLAPARNEFFNEKCYNLQGKCQSSCAKNEELVALCWKNLKCCVKIKPCKKIREQD
    

Molecular Weight7963.42 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.0663

GRAVY Index-0.05

Hydrophobic Moment 0.48

Boman Index0.02

Instability Index39.09

Aliphatic Index 72.84

Aromaticity 0.1642

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3005.34

LogP -19.85

H-bond Donors 108.0

H-bond Acceptors 105.0

Rotatable Bonds 267.0

Heavy Atoms 557.0

Ring Count 15.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0274521 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence