Peptide Database

Peptide NameNPP

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC248H370N76O77S2

DescriptionStandard

        PDLSAETPVFPGNCDEQPLTENPRKYVMGHFRWDRFGRRNGSSSFGAGGAAQ
    

Molecular Weight5712.18 Da

Isoelectric Point (pI)7.14

Net Charge (pH 7.0)0.05

Net Charge (pH 7.4) -0.09

Charge Density (pH 7.0) 0.0009

GRAVY Index-0.90

Hydrophobic Moment 0.73

Boman Index-0.13

Instability Index50.98

Aliphatic Index 33.85

Aromaticity 0.1154

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2459.12

LogP -30.88

H-bond Donors 86.0

H-bond Acceptors 80.0

Rotatable Bonds 180.0

Heavy Atoms 403.0

Ring Count 13.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063352 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyPOMC

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhe36 Amidation

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0268477 VERIFIED: NO