Peptide Database

Peptide NameNeuropeptide AF36+O2

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC54H88N14O15S2

DescriptionStandard

        VPSAADMMIRF
    

Molecular Weight1237.49 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-0.26

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) -0.0241

GRAVY Index0.77

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index33.77

Aliphatic Index 80.00

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 464.96

LogP -3.03

H-bond Donors 16.0

H-bond Acceptors 17.0

Rotatable Bonds 38.0

Heavy Atoms 85.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307420 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyFMRFamide related peptide

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsMet7 oxidation; Met8 oxidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0331996 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyNeuropeptide AF36

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0414535 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/