Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length572 amino acids

Chemical FormulaC2756H4353N805O841S21

DescriptionStandard

        MGYRPDIHGRGKALSCDKTTTGARLIPSISLTNYNVYGYGVIRNGDKTTPCPTCGKPGTVVEGDPRWTIHGTAVAVDRGIVRCDCPYGSNRIIAPLGQWMGAAPSPEQIAAEKQAAFLAQRKTEQEAEEKRLAEERERNRVFAKSCLRGEGCNDAGGQREPHNNFAEMSFFRAAPPADAATDTDAPQHAQTAKKKPQRPEDIPKPKKRSALWKWLNGNHEEMDYQAAVATATAATRAQAATAGASSLELLGGRTLTYGTWAVRGAAGLGEVAAAGAGASVAGLLIGMMPGRLNDGEQDFIDRMRAVQMQEVPTRVRFTWETDASGNPTPHGWHTQPGKDMVRVRKMAWDSRYQAYTFTTEEEPRITIVWTPDHSGVSVPSNTGNQARPVLPNPVIVDPLPDNTSITATTSPAPEEKNFADYILILPLPDLPPIYIYLSKPPVEFLEVELYSDFKRRSRQEKYEVDHMPSAAAARAYLRKKYPKLDTKQLDRMAEDVAAIVVPKEVHQKLSETYGGRNKPAQIEQDSLNLRAAADRNLDAVKPALKEHGATEFQIEAARVKMHELNNEMGLYK
    

Molecular Weight62893.30 Da

Isoelectric Point (pI)8.03

Net Charge (pH 7.0)2.57

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0045

GRAVY Index-0.59

Hydrophobic Moment 0.74

Boman Index-0.08

Instability Index40.23

Aliphatic Index 68.86

Aromaticity 0.0682

Extinction Coeff. Reduced 76320.00

Extinction Coeff. Oxidized 76695.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376401 VERIFIED: YES

Provenance & Taxonomy

OrganismCitrobacter amalonaticus [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)