Peptide Database

Peptide NameCrustacean hyperglycemic hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC366H556N98O116S8

DescriptionStandard

        QIYDTSCKGVYDRGLFSDLEHVCDDCYNLYRNSYVASACRSNCYSNVVFRQCMEELLLMDEFDKYARAVQIV
    

Molecular Weight8441.44 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-4.20

Net Charge (pH 7.4) -4.57

Charge Density (pH 7.0) -0.0584

GRAVY Index-0.23

Hydrophobic Moment 0.68

Boman Index-0.05

Instability Index40.55

Aliphatic Index 77.08

Aromaticity 0.1389

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3514.79

LogP -34.47

H-bond Donors 129.0

H-bond Acceptors 121.0

Rotatable Bonds 278.0

Heavy Atoms 588.0

Ring Count 11.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405005 VERIFIED: YES

Provenance & Taxonomy

OrganismCancer pagurus [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6755

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour