Peptide Database

Peptide NameSLAY-screened peptide P2990

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC93H159N33O33

DescriptionStandard

        ALAARSRVTEQTDRTNDIHL
    

Molecular Weight2267.46 Da

Isoelectric Point (pI)6.80

Net Charge (pH 7.0)-0.11

Net Charge (pH 7.4) -0.35

Charge Density (pH 7.0) -0.0056

GRAVY Index-0.77

Hydrophobic Moment 0.56

Boman Index-0.30

Instability Index51.00

Aliphatic Index 88.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1109.60

LogP -14.69

H-bond Donors 40.0

H-bond Acceptors 34.0

Rotatable Bonds 76.0

Heavy Atoms 159.0

Ring Count 1.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389177 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/