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MYP_023760
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Basic Information
kalata B12
Anticancer
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C117H183N31O43S6
Standard
Sequence
GSLCGDTCFVLGCNDSSCSCNYPICVKD
Physicochemical Analysis
2904.28 Da
4.17
-2.29
-2.59
-0.0820
0.32
0.17
0.14
42.00
62.50
0.0714
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1185.71
-17.24
46.0
47.0
91.0
197.0
3.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014180 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclotide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0078589 VERIFIED: NO
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-18; 8-20; 13-25
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0110935 VERIFIED: NO
Provenance & Taxonomy
Oldenlandia affinis DC [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17534989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17534989/
RECORD: Rec_0188239 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17534989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17534989/
RECORD: Rec_0206719 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclotide
60225
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antifungal Insecticidal
PMID17534989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17534989/
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