Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC847H1380N244O251S8

DescriptionStandard

        MKTQMDGHSLGRWSLVLLLLGLVMPLAIVAQVLSYKEAVLHAIDGINQRSSDANLYRILDLDPSLTMDGDPDTPKPVSFTVKETVCPRRTQQSPEDCDFKKDGLVKRCVGTVTLNQARGSFDISCDKDNRRFALLGDFFRKAREKIGEEFKRIVQRIKDFLRNLVPRTES
    

Molecular Weight19254.02 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)3.66

Net Charge (pH 7.4) 3.24

Charge Density (pH 7.0) 0.0215

GRAVY Index-0.34

Hydrophobic Moment 0.97

Boman Index-0.10

Instability Index40.07

Aliphatic Index 91.12

Aromaticity 0.0647

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8044.83

LogP -86.27

H-bond Donors 284.0

H-bond Acceptors 265.0

Rotatable Bonds 654.0

Heavy Atoms 1350.0

Ring Count 22.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010174 VERIFIED: YES

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetBacillus megaterium

RECORD: Rec_0229365 VERIFIED: YES