Peptide Database

Peptide NameGhrelin-28

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC134H222N44O42S2

DescriptionStandard

        GLTFLSPADMQKIAERQSQNKLRHGNMN
    

Molecular Weight3185.60 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0660

GRAVY Index-0.95

Hydrophobic Moment 0.53

Boman Index-0.22

Instability Index69.76

Aliphatic Index 62.86

Aromaticity 0.0357

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1438.58

LogP -17.89

H-bond Donors 48.0

H-bond Acceptors 47.0

Rotatable Bonds 111.0

Heavy Atoms 222.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053236 VERIFIED: YES

Provenance & Taxonomy

OrganismAquarana catesbeiana [Animal]

FamilyGhrelin

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0334024 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeiana [Animal]

FamilyMotilin

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Gastrointestinal

RECORD: Rec_0336341 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/