Peptide Database

Peptide NameT3-R9

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC111H204N48O25S

DescriptionStandard

        AIVKLTVYDCIRRRRRRRRR
    

Molecular Weight2643.18 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.79

Net Charge (pH 7.4) 8.58

Charge Density (pH 7.0) 0.4392

GRAVY Index-1.22

Hydrophobic Moment 0.56

Boman Index-0.90

Instability Index236.76

Aliphatic Index 92.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1277.10

LogP -12.69

H-bond Donors 53.0

H-bond Acceptors 35.0

Rotatable Bonds 93.0

Heavy Atoms 185.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0006929 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays