Peptide Database

Peptide NameHepcidin-2 (Hepcidin-2 protein)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC421H670N112O128S12

DescriptionStandard

        MKTVRVAAAVALLFAFVWIQESSAQADAQMEEMEGPEDVDIPVELKVEEVSVDAMTSPYYRSREKRGIKCKFCCGCCTPGVCGLCCRF
    

Molecular Weight9733.28 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-3.56

Net Charge (pH 7.4) -3.92

Charge Density (pH 7.0) -0.0404

GRAVY Index0.11

Hydrophobic Moment 0.41

Boman Index0.05

Instability Index39.42

Aliphatic Index 74.20

Aromaticity 0.0795

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3831.72

LogP -35.59

H-bond Donors 140.0

H-bond Acceptors 137.0

Rotatable Bonds 321.0

Heavy Atoms 673.0

Ring Count 12.0

Amide Bonds 90.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0325846 VERIFIED: NO

Provenance & Taxonomy

OrganismBoleophthalmus pectinirostris [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0394783 VERIFIED: NO