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MYP_023660
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Basic Information
Dermaseptin-H5 (Dermaseptin-like peptide 5, DMS5; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
25 amino acids
C111H188N30O32
Standard
Sequence
GLWSTIKNVGKEAAIAAGKAVLGSL
Physicochemical Analysis
2454.86 Da
9.70
1.76
1.55
0.0704
0.57
0.60
0.30
5.49
121.20
0.0400
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
996.65
-9.58
35.0
34.0
83.0
173.0
2.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0231746 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa azurea [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 11775
0.5 μM
MIC
PMID17553595 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17553595/
RECORD: Rec_0241272 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa azurea [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus ATCC 49732
2.0 μM
MIC
PMID17553595 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17553595/
RECORD: Rec_0244566 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa hypochondrialis azurea [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0298981 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Dermaseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
0.5 μM
MIC
PaperA.H. Thompson et al. / Peptides 28 (2007) 1331-1343. A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea
RECORD: Rec_0332704 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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