Peptide Database

Peptide NamePeptide 17

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC115H190N42O28S2

DescriptionStandard

        KRKKHRCRVYNNGLPTGLSRWC
    

Molecular Weight2673.13 Da

Isoelectric Point (pI)11.01

Net Charge (pH 7.0)6.82

Net Charge (pH 7.4) 6.53

Charge Density (pH 7.0) 0.3102

GRAVY Index-1.33

Hydrophobic Moment 0.48

Boman Index-0.49

Instability Index53.79

Aliphatic Index 48.64

Aromaticity 0.0909

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1182.63

LogP -12.84

H-bond Donors 46.0

H-bond Acceptors 38.0

Rotatable Bonds 89.0

Heavy Atoms 187.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191175 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus ATCC 6538

Activity2.1 μM

MethodMIC