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MYP_023582
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Basic Information
[Tyr3]Octreotide
Anticancer
Standard
7 amino acids
C45H59N9O10S2
Standard
Sequence
FCYWKTC
Physicochemical Analysis
950.13 Da
8.05
0.74
0.50
0.1055
0.14
0.25
0.18
-6.24
0.00
0.4286
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
320.19
-0.41
14.0
13.0
26.0
66.0
4.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095118 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Somatostatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 3-(2-propyn-1-yloxy)-, S-[(2,4,6-trimethoxyphenyl)methyl] benzenecarbothioic acid ester
Bio-Activity Profile
Anticancer
PaperSynthesis of DOTA-Conjugated Multimeric [Tyr3]Octreotide Peptides via a Combination of Cu(I)-Catalyzed "Click"" Cycloaddition and Thio Acid/Sulfonyl Azide ""Sulfo-Click"" Amidation and Their in Vivo Evaluation". Journal of Medicinal Chemistry. 2010 Evidence URLhttps://doi.org/10.1021/jm100246m
RECORD: Rec_0244492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Somatostatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) derivative
Bio-Activity Profile
Anticancer
PaperSynthesis of DOTA-Conjugated Multimeric [Tyr3]Octreotide Peptides via a Combination of Cu(I)-Catalyzed "Click"" Cycloaddition and Thio Acid/Sulfonyl Azide ""Sulfo-Click"" Amidation and Their in Vivo Evaluation". Journal of Medicinal Chemistry. 2010 Evidence URLhttps://doi.org/10.1021/jm100246m
RECORD: Rec_0293904 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Somatostatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 3,5-bis(2-propyn-1-yloxy)-, S-[(2,4,6-trimethoxyphenyl)methyl] benzenecarbothioic acid ester
Bio-Activity Profile
Anticancer
PaperSynthesis of DOTA-Conjugated Multimeric [Tyr3]Octreotide Peptides via a Combination of Cu(I)-Catalyzed "Click"" Cycloaddition and Thio Acid/Sulfonyl Azide ""Sulfo-Click"" Amidation and Their in Vivo Evaluation". Journal of Medicinal Chemistry. 2010 Evidence URLhttps://doi.org/10.1021/jm100246m