Peptide Database

Peptide NameApl_AvBD-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC201H324N66O48S7

DescriptionStandard

        PGLSSPRRDMLFCRKGSCHFGRCPIHLIKVGRCFGFRSCCK
    

Molecular Weight4657.59 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)8.07

Net Charge (pH 7.4) 7.82

Charge Density (pH 7.0) 0.1969

GRAVY Index-0.14

Hydrophobic Moment 0.62

Boman Index-0.13

Instability Index68.77

Aliphatic Index 54.63

Aromaticity 0.0976

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1820.79

LogP -19.08

H-bond Donors 74.0

H-bond Acceptors 65.0

Rotatable Bonds 153.0

Heavy Atoms 322.0

Ring Count 9.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399906 VERIFIED: YES

Provenance & Taxonomy

OrganismCalypte anna [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)